Single dose Ebola vaccine is safe, effective in monkeys against outbreak strain

A single dose of an experimental Ebola virus vaccine completely protects cynomolgus macaques against the current EBOV outbreak strain, EBOV-Makona, when given at least seven days before exposure, and partially protects them if given three days prior, scientists report. The live-attenuated vaccine, VSV-EBOV, uses genetically engineered vesicular stomatitis virus to carry an EBOV gene that has safely induced protective immunity in macaques.